![]() ![]() Progressive alopecia areata is associated with severe social and emotional impact.Īlopecia areata mostly presents as a sudden loss of hair in well demarcated localized areas. The condition is thought to be self-limited in majority of cases, but in some the disease has a progressive course and needs active treatment in the form of oral or topical therapeutic options. Histopathologically, alopecia areata is characterized by an increase in the number of catagen and telogen follicles and the presence of perifollicular lymphocytic infiltrate around the anagen phase hair follicles. Both the sexes are equally affected and there is no racial variation reportedClinically, alopecia areata may present as a single well demarcated patch of hair loss, multiple patches, or extensive hair loss in the form of total loss of scalp hair (alopecia totalis) or loss of entire scalp and body hair (alopecia universalis). The disease can begin at any age, but the peak incidence is between 20 and 50 years of age 5. The term ‘alopecia areata’ was first used for this disorder by Savages 1.Alopecia areata has a reported incidence of 0.1-0.2%, with a life-time risk of 1.7% 2-4. Although the etiopathogenesis of alopecia areata is still unknown, the most widely accepted hypothesis is that it is a T-cell mediated autoimmune condition that occurs in genetically predisposed individuals. Keywords: Alopecia areata, treatment, autoimmune, corticosteroids, recent advances, contact sensitizersĪlopecia areata is a non-scarring autoimmune, inflammatory hair loss affecting the scalp and/or body. Various therapeutic approaches are presently available for managing alopecia areata including corticosteroids, contact sensitizers and immunosuppressants, but none have been shown to alter the course of the disease on a consistent basis. This disorder occurs in both the sexes, in all age groups, and is characterized by the sudden appearance of circumscribed areas of hair loss on the scalp or other parts of the body. In both cases, the effectiveness of these treatment types can vary depending on the person and may be long term to ensure hair continues to grow.Cite this article as: BJMP 2012 5(3):a530Īlopecia areata is a common, non-scarring, autoimmune disorder affecting any hair-bearing area. The difference is, treatments for AT are focused on regrowing the hair lost on the scalp, whereas treating AU requires targeting hair follicles on the entire body. Now you are familiar with some of the treatment options for AU, how about Alopecia Totalis? This subtype is also treated using the same treatment types listed above. Whether a specific treatment is suitable for a child is left to the discretion of the dermatologist, and the comfort level of the parents and child. JAK inhibitors (baricitinib, tofacitinib, ruxolitinib)įor children, treatment options are less extensive.immunosuppressive medications (methotrexate, cyclosporine).corticosteroids (topical steroids, steroid injections, prednisone, clobetasol).topical immunotherapy such as diphencyprone (DPCP) or squaric acid (SADBE).For adults with AU, common treatment options include: What course of treatment your dermatologist recommends will be dependent on what subtype of Alopecia Areata you have. There is currently no cure for Alopecia Areata but there are a variety of treatment options. ![]()
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